AMIS : Anthropologie Moléculaire et Imagerie de Synthèse

304 Résultats

• article

  Combined effects of Gm - Km immunoglobulin allotypes and age on IgG and subclass responses to Plasmodium falciparum VarO rosetting variant in Benin

  Migot-Nabias F, Lokossou, I. Vigan-Womas I, Guitard E, Guillotte M, Mercereau-Pujalon O, Dugoujon JM , Garcia A

  sous presse. Microbes and Infection

• article

  Gene-culture Dynamics: An Example Involving Native Americans

  Hunemeier T, Acuna V, Contini V, Rothammer F, Dugoujon JM , Mazieres S , Corral–Montanes P, Rodrigues Paixo-Cortes V, Salzano FM, Canizales-Quinteros S, Ruiz-Linares A, Catira Bortoloni M

  sous presse. Am J of Phys Anthropol.

• article

  mtDNA and Y-chromosome diversity in Aymaras and Quechuas from Bolivia: different stories and especial genetic traits of the Andean Altiplano populations.

  Dugoujon JM , Bravi C, Vasquez R, Villena M, Tonasso L, Gerbault P, Saenz N, Moral P, Gaya-Vidal M

  sous presse. Am J Phys Anthropol.

• article

  French Guiana Amerindian demographic history as revealed by autosomal and Y-Chromosome STRs

  Crubezy E , Bois E, Larrouy G , Dugoujon JM , Crossetti SG, Callegari-Jacques SM, Mazieres S , Hutz MH, Salzano FM

  2011. Annals of Human Biology 38(1):76-83

• article

  Immunogenetics as a tool in anthropological studies

  Sanchez-Mazas A, Fernandez-Vi_a M, Middleton D, Hollenbach J, Buhler S, Di D, Rajalingam R, Dugoujon JM , Mack S, Thorsby E

  2011. Immunology 2011 Apr 11. doi:10.1111/j.1365-2567.2011.03438.x. [Epub ahead of print]

• article

  3D automated quantification of asymmetries on fossil endocasts.

  Combes, B, Braga, J , Thackeray, F, Prima, S

  2010.

• article

  3D automatic methods to segment "virtual" endocasts: state of the art and future directions.

  Subsol, G, Gesquiere, G, Braga, J , Thackeray, F

  2010.

• article

  A Predominantly Neolithic Origin for European Paternal Lineages

  Balaresque, P. , Bowden, G. R., Adams, S. M., Leung, H. Y., King, T. E., Rosser, Z. H., Goodwin, J., Moisan, J. P., Richard, C., Millward, A., Demaine, A. G., Barbujani, G., Previdere, C., Wilson, I. J., Tyler-Smith, C., Jobling, M. A.

  2010. Plos Biology Vol.1 n°8

  The relative contributions to modern European populations of Paleolithic hunter-gatherers and Neolithic farmers from the Near East have been intensely debated. Haplogroup R1b1b2 (R-M269) is the commonest European Y-chromosomal lineage, increasing in frequency from east to west, and carried by 110 million European men. Previous studies suggested a Paleolithic origin, but here we show that the geographical distribution of its microsatellite diversity is best explained by spread from a single source in the Near East via Anatolia during the Neolithic. Taken with evidence on the origins of other haplogroups, this indicates that most European Y chromosomes originate in the Neolithic expansion. This reinterpretation makes Europe a prime example of how technological and cultural change is linked with the expansion of a Y-chromosomal lineage, and the contrast of this pattern with that shown by maternally inherited mitochondrial DNA suggests a unique role for males in the transition.

• article

  A predominantly neolithic origin for European paternal lineages

  Balaresque, Patricia , Bowden, Georgina R., Adams, Susan M., Leung, Ho-Yee, King, Turi E., Rosser, Zoe H., Goodwin, Jane, Moisan, Jean-Paul, Richard, Christelle, Millward, Ann, Demaine, Andrew G., Barbujani, Guido, Previdere, Carlo, Wilson, Ian J., Tyler-Smith, Chris, Jobling, Mark A.

  2010. PLoS Biol Vol.1 n°8

  The relative contributions to modern European populations of Paleolithic hunter-gatherers and Neolithic farmers from the Near East have been intensely debated. Haplogroup R1b1b2 (R-M269) is the commonest European Y-chromosomal lineage, increasing in frequency from east to west, and carried by 110 million European men. Previous studies suggested a Paleolithic origin, but here we show that the geographical distribution of its microsatellite diversity is best explained by spread from a single source in the Near East via Anatolia during the Neolithic. Taken with evidence on the origins of other haplogroups, this indicates that most European Y chromosomes originate in the Neolithic expansion. This reinterpretation makes Europe a prime example of how technological and cultural change is linked with the expansion of a Y-chromosomal lineage, and the contrast of this pattern with that shown by maternally inherited mitochondrial DNA suggests a unique role for males in the transition.

• article

  Complete mitochondrial DNA sequences provide new insights into the Polynesian motif and the peopling of Madagascar

  Tonasso L, Guitard E, Randriamarolaza LP, Dugoujon JM , Mormina M, Cox MP, Ricaut FX , Razafindrazaka H , Ludes B , Crubezy E.

  2010. Eur J Hum Genet. 2010 May:18(5):575-581

• article

  Complete mitochondrial DNA sequences provide new insights into the Polynesian motif and the peopling of Madagascar

  Razafindrazaka, H , Ricaut, FX , Cox, MP, Mormina, M, Dugoujon, JM , Randriamarolaza, LP, Guitard, E, Tonasso, L, Ludes, B , Crubezy, E

  2010. EUROPEAN JOURNAL OF HUMAN GENETICS

  More than a decade of mitochondrial DNA (mtDNA) studies have given the 'Polynesian motif' renowned status as a marker for tracing the late-Holocene expansion of Austronesian speaking populations. Despite considerable research on the Polynesian motif in Oceania, there has been little equivalent work on the western edge of its expansion - leaving major issues unresolved regarding the motif's evolutionary history. This has also led to considerable uncertainty regarding the settlement of Madagascar. In this study, we assess mtDNA variation in 266 individuals from three Malagasy ethnic groups: the Mikea, Vezo, and Merina. Complete mtDNA genome sequencing reveals a new variant of the Polynesian motif in Madagascar; two coding region mutations define a Malagasy-specific sub-branch. This newly defined 'Malagasy motif' occurs at high frequency in all three ethnic groups (13-50

• article

  Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations

  Dugoujon JM , Excoffier L, Bortolini MC, Salzano FM, Labuda D, Rothhammer F, Llop E, Barrantes R, Klitz W, Tsuneto LT, Petzl-Erler ML, Hurtado AM, Hill K, Poletti G, Gallo C, Molina JA, Parra MV, Rojas W, Bedoya G, Burley MW, Wang S, Ray N, Bravi C, Mazieres S , Yang NN, Ruiz-Linares A

  2010. Ann Hum Genet. 74(6):525-538

• article

  Different evolutionary histories of the coagulation factor VII gene in human populations?

  Bissar-Tadmouri N, Chaabani H, Moschonas N, Dugoujon JM , Gaya-Vidal M, Esteban E, Athanasiadis G, Harich N, Stoneking M, Moral P

  2010. Ann Hum Genet. 2010 Jan;74(1):34-45.

• article

  Fetal and infant growth patterns of the mandibular symphysis in modern humans and chimpanzees (Pan troglodytes)

  Coquerelle, M , Bookstein, FL, Braga, J , Halazonetis, DJ, Weber, GW

  2010.

  Comparison of the early development of the mandibular symphysis between primates and modern humans is of particular interest in human palaeontology. Using geometric morphometric methods, we explored and compared the ontogenetic shape changes of 14 chimpanzee mandibles (Pan troglodytes) against 66 human CT-scanned mandibles over the age range from fetal life to the complete emergence of the deciduous dentition in a visualization incorporating the deciduous tooth arrangement. The results reveal that the symphysis is anteriorly inclined in the youngest chimpanzee fetuses but develops an increasingly vertical orientation up until birth. At the same time, the anterior teeth reorient before a vertical emergence, and a symphyseal tuber appears on the labial side. When the deciduous canine emerges, the symphysis inclines anteriorly again, exhibiting the adult characteristic slope. These two phases are characterized by a repositioning of the simian shelf. Unlike chimpanzees, the human symphysis remains vertical throughout fetal development. However, the combination of morphological changes observed in chimpanzee fetuses is similar to that of modern humans after birth, as the mental region projects forward. By elongating the alveolar process, the inclination of the chimpanzee symphysis could be a key event for emergence of the deciduous canine, as space is lacking at the alveolar ridge in a vertical symphysis once the deciduous incisors and molars have emerged. The repositioning of the simian shelf suggests that the suprahyoid muscles have a significant influence on the anterior growth of the symphysis. The anteroposterior positioning of the basal symphysis in both species may be related to hyoid bone position during ontogeny.

• article

  Human evolution in Siberia: from frozen bodies to ancient DNA

  Crubezy, E , Amory, S, Keyser, C , Bouakaze, C, Bodner, M, Gibert, M , Rock, A, Parson, W, Alexeev, A, Ludes, B

  2010. BMC EVOLUTIONARY BIOLOGY

  Background: The Yakuts contrast strikingly with other populations from Siberia due to their cattle- and horse-breeding economy as well as their Turkic language. On the basis of ethnological and linguistic criteria as well as population genetic studies, it has been assumed that they originated from South Siberian populations. However, many questions regarding the origins of this intriguing population still need to be clarified ( e. g. the precise origin of paternal lineages and the admixture rate with indigenous populations). This study attempts to better understand the origins of the Yakuts by performing genetic analyses on 58 mummified frozen bodies dated from the 15(th) to the 19(th) century, excavated from Yakutia ( Eastern Siberia).|Results: High quality data were obtained for the autosomal STRs, Y-chromosomal STRs and SNPs and mtDNA due to exceptional sample preservation. A comparison with the same markers on seven museum specimens excavated 3 to 15 years ago showed significant differences in DNA quantity and quality. Direct access to ancient genetic data from these molecular markers combined with the archaeological evidence, demographical studies and comparisons with 166 contemporary individuals from the same location as the frozen bodies helped us to clarify the microevolution of this intriguing population.|Conclusion: We were able to trace the origins of the male lineages to a small group of horse-riders from the Cis-Baikal area. Furthermore, mtDNA data showed that intermarriages between the first settlers with Evenks women led to the establishment of genetic characteristics during the 15(th) century that are still observed today.

• article

  Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages

  Dugoujon JM , Colomb EB, Watson E, Destro-Bisol G, Massaia A, Sellitto D, Trombetta B, Cruciani F, Moral P, Scozzari R

  2010. Eur J Hum Genet. 2010 Jul;18(7):800-807

• article

  Incisor and Molar Root Morphology of the Juvenile Neanderthal from Scladina Cave (Belgium).

  Le Cabec, A , Kupczik, K, Toussaint, M, Braga, J , Hublin, JJ

  2010.

• article

  Measuring the inter-species variability of endocast growth using shape regression and spatiotemporal registration.

  Durrleman, S, Pennec, X, Trouve, A, Ayache, N, Braga, J

  2010.

• Article

  Mechanical Analysis of Feeding Behavior in the Extinct "Terror Bird" Andalgalornis steulleti (Gruiformes: Phorusrhacidae)

  Degrange FJ, Tambussi CP, Moreno K , Witmer LM, Wroe S

  2010. PLOS One 5: e11856.

  Consulter

• article

  Multislice Computed Tomography of the First Rib: A Useful Technique for Bone Age Assessment

  Moskovitch, G, Dedouit, F , Braga, J , Rouge, D , Rousseau, H, Telmon, N

  2010.

  Macroscopic study of the first rib has been described by Kunos et al. as an efficient method of age estimation. We retrospectively reviewed a test sample of 160 first right ribs obtained from multislice computed tomography (MSCT) clinical investigations of living individuals aged 15-30 years old. Based on the descriptions of Kunos et al., we analyzed the morphological appearance of the sternal end of the first rib on two- and three-dimensional MSCT reconstructions and defined changes in appearance in stages (from 2 to 5). We also studied the calcification and ossification of the costal cartilage as an independent feature. By statistical analysis (ANOVA), we determined for each gender the correlation between the estimated stage of the costal face, the appearance of the costal cartilage, and the documented age of the subjects. We demonstrated that MSCT of the first rib appears to be an efficient noninvasive modality for bone age estimation.

• article

  Paleogenetical study of pre-Columbian samples from Pampa Grande (Salta, Argentina)

  Ludes B , Bravi CM, Dugoujon JM , Dejean CB, Keyser C , Mendisco F , Carnese FR, Crubezy E

  2010. Am J Phys Anthropol. 2010 Mar;141(3):452-462

• article

  Paleogenetical Study of Pre-Columbian Samples From Pampa Grande (Salta, Argentina)

  Carnese, FR, Mendisco, F , Keyser, C , Dejean, CB, Dugoujon, JM , Bravi, CM, Ludes, B , Crubezy, E

  2010. AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

  Ancient DNA recovered from 21 individuals excavated from burial sites in the Pampa Grande (PG) region (Salta province) of North-Western Argentina (NWA) was analyzed using various genetic markers (mitochondrial DNA, autosomal STRs, and Y chromosomal STRs). The results were compared to ancient and modern DNA from various populations in the Andean and North Argentinean regions with the aim of establishing their relationships with PG. The mitochondrial haplogroup frequencies described (11

• article

  Paleogenetical study of pre-Columbian samples from Pampa Grande (Salta, Argentina).

  Carnese F.R., Mendisco F. , Keyser C. , Dejean C.B., Dugoujon J.M. , Bravi C.M., Ludes B. , Crubezy E.

  2010. American Journal of Physical Anthropology. 141 :452-462.

• article

  PopAffiliator: online calculator for individual affiliation to a major population group based on 17 autosomal short tandem repeat genotype profile

  Zhivotovsky L, Zeng Z, Rangel Villalobos H, Takeshita H, Prieto L, Perone C, Parson W, Mertens G, Gonzalez-Martin A, Marian C, Immel UD, Hadi S, Gonzalez-Andrade F, Espinoza M, Dugoujon JM , Coudray C, Cho NS, Chantratita W, Ballard R, Andreassen R, Alshamali F, Pereira L, Camacho R, Fonseca NA

  2010. Int J Legal Med. 2010 Jun 16. [Epub ahead of print]

• Announcement of Population Data

  Population genetics of 17 Y-chromosomal STR loci in Yakutia

  Morgane Gibert., Eric CrubEzy, AndrE Sevin, Anatoly N. Alekseev, Innokentevich V. Timofeev, Larissa E. Evdokimova, Patricia Balaresque , Catherine ThEves

  2010. Forensic Sci Int Genet. 2010 Oct;4(5):e129-30.

• article

  Population relationships in the Mediterranean revealed by autosomal geneticdata (Alu and Alu/STR compound systems)

  Bissar-Tadmouri N, Harich N, Kandil M, Fuster V, Mesa MS, Luna F, Dugoujon JM , Athanasiadis G, Gaya-Vidal M, Via M, Esteban E, Gonzalez-Perez E, Saetta A, Moral P

  2010. Am J Phys Anthropol. 2010 Mar;141(3):430-439

• article

  Reply to Lancaster

  Dugoujon JM , Colomb EB, Watson E, Destro-Bisol G, Massaia A, Sellitto D, Trombetta B, Cruciani F, Moral P, Scozzari R

  2010. Eur J Hum Genet. 2010 Jun 23. [Epub ahead of print]

• article

  Response to cruciani et Al

  Rosser, Zoe H., Balaresque, Patricia , Jobling, Mark A.

  2010. Am J Hum Genet Vol.3 n°86

• article

  Searching the peopling of the Iberian Peninsula from the perspective of two Andalusian subpopulations: a study based on Y-chromosome haplogroups J and E

  Ambrosio B, Hernandez C, Noveletto A, Dugoujon JM , Rodriguez JN, Cuesta P, Fortes-Lima C, Caderon R

  2010. Collegium Antropologicum 34(4):1215-1228

• article

  The Andalusian population from Huelva reveals a high diversification of Y-DNA paternal lineages from haplogroup E: Identifying human male movements within the Mediterranean space

  Novelletto A, Fortes-Lima CA, Gonzalez-Martin A, De La Fuente D, Hernandez C, Dugoujon JM , Ambrosio B, Rodriguez JN, Calderon R.

  2010. Ann Hum Biol. 2010 Jan-Feb;37(1):86-107